In-Sens

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  • IN-SENS Program
    • Goals
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    • Students
      • ESR1 Rita Marreiros
      • ESR2 Daniela Moutinho
      • ESR3 Eshan Bundhoo
      • ESR4 Marion Bonneau
      • ESR5 Miguel Ángel González Lozano
      • ESR6 Martina Rosato
      • ESR7 Benedetta Fazari
      • ESR8 Karola Käfer
      • ESR9 Elena Marchisella
      • ESR10 Marcello Venzi
      • ESR11 Vishal Sinha
      • ESR12 David Just
      • ESR13 Nirmal Raman Kannaiyan
      • ESR14 Tarik Dahoun
      • ESR15 Yogesh Paudel
  • Research
    • Research Team 1
    • Research Team 2
    • Research team 3
    • Research Team 4
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Research

insens-research-groupIN-SENS is an interdisciplinary, cutting-edge European industry-academia collaborative effort for a novel training of scientists in molecular psychiatry with the prospect of discovering the biology of schizophrenia and actively promote drug discovery. Mental illnesses are a major burden to patients, relatives, and public health worldwide. IN-SENS therefore aims to profoundly change the academic-industry research landscape in European psychiatry by an unprecedented, innovative strategy.

in-sens-workflow

The extended intra- and intercellular signalling pathway of disrupted-in-schizophrenia 1 (DISC1), the best characterized gene known to cause schizophrenia and other chronic mental illnesses (CMI), will be used as a molecular Rosetta stone for this purpose.

Focussing on the extended DISC1 pathway in its different aspects, including clinical psychiatry nucleates research and avoids the outspreading of research groups. IN-SENS forms a novel infrastructure and an interweaved network of research groups, ESRs and industry maximizing lateral transfer of knowledge and promoting the emergence of novel products, like novel diagnostic and therapeutic targets or tools.

IN-SENS has formed 4 research teams. The trainees of these research teams will be working across the different laboratories with obligatory secondments, thus enabling them to create a multidisciplinary working attitude.

  • Research Team 1: Molecular and cellular biology
  • Research Team 2: Functional modelling of the extended DISC1 pathway
  • Research Team 3: Genetics & Diagnostics
  • Research Team 4: Translation of DISC1 pathways into human mental illness

Groundbreaking: DISC1opathies

A novel subgroup of CMD diseases

evelyn.van.royen@sylics.com | T +31 20 598 28 06 | M +31 6 46 06 46 05
This project is funded by the EC under FP7-PEOPLE-2013 (607616)

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